Formulation of Tioconazole and Melaleuca alternifolia Essential Oil Pickering Emulsions for Onychomycosis Topical Treatment
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چکیده
منابع مشابه
Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream.
The prevalence of onychomycosis, a superficial fungal infection that destroys the entire nail unit, is rising, with no satisfactory cure. The objective of this randomized, double-blind, placebo-controlled study was to examine the clinical efficacy and tolerability of 2% butenafine hydrochloride and 5% Melaleuca alternifolia oil incorporated in a cream to manage toenail onychomycosis in a cohort...
متن کاملIn vitro antiviral activity of Melaleuca alternifolia essential oil.
AIMS To investigate the in vitro antiviral activity of Melaleuca alternifolia essential oil (TTO) and its main components, terpinen-4-ol, alpha-terpinene, gamma-terpinene, p-cymene, terpinolene and alpha-terpineol. METHODS AND RESULTS The antiviral activity of tested compounds was evaluated against polio type 1, ECHO 9, Coxsackie B1, adeno type 2, herpes simplex (HSV) type 1 and 2 viruses by ...
متن کاملMelaleuca (Melaleuca alternifolia) essential oil demonstrates tissue-remodeling and metabolism-modulating activities in human skin cells
Melaleuca (Melaleuca alternifolia) essential oil (MEO), commonly known as tea tree oil, is popularly used in skincare products. In the current study, we investigated the biological activity of a commercially available MEO (with terpinen-4-ol as the major active component) in pre-inflamed human dermal fibroblasts, which were designed to simulate chronic inflammation. We analyzed the levels of se...
متن کاملActivity of Tea Tree (Melaleuca alternifolia) Essential Oil against L3 Larvae of Anisakis simplex
Nematicidal activity of Melaleuca alternifolia essential oil, commonly known as tea tree oil (TTO), was assayed in vitro against L3 larvae of Anisakis simplex. The results showed a mortality of 100% for concentrations between 7 and 10 μL/mL after 48 h of incubation, obtaining an LD50 value of 4.53 μL/mL after 24 hours and 4.27 μL/mL after 48 hours. Concentration-dependent inhibition of acetylch...
متن کاملEssential oil of Melaleuca alternifolia for the treatment of oral candidiasis induced in an immunosuppressed mouse model
BACKGROUND The search for alternative therapies for oral candidiasis is a necessity and the use of medicinal plants seems to be one of the promising solutions. The objective of this study was to evaluate the in vitro and in vivo effects of the essential oil of Melaleuca alternifolia on Candida albicans. METHODS The minimum inhibitory concentration (MIC) and minimum biofilm eradication concent...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules25235544